Clinical trials (indication, phase) |
Date (year) |
Protocol nb: E7080-G000-604 EISAI
An open-label, multi-center, roll-over study to assess long term safety of Lenvatinib monotherapy or Lenvatinib combination regimen or comparator treatment arm to cancer patients in Eisai sponsored Lenvatinib trials |
2016 – 2022
2 patients |
STUDY No. TST-EFS-04-MPP/16 Mattern
Efficacy and safety of two- or three-times daily intranasal administration of testosterone gel (Tescum) in adult hypogonadal male patients, divided in 2 cohorts (cohort 1 – efficacy and long term safety assessment, cohort 2 – long term safety assessment) |
2017- 2020
40 patients randomized |
Protocol nb: XL184–401 EXELIXIS
A Randomized, Double-blind Study to Evaluate the Efficacy and Safety of Cabozantinib (XL184) at 60 mg/Day Compared to 140 mg/Day in Progressive, Metastatic Medullary Thyroid Cancer Patients |
2018 –
13 patients randomized |
Protocol Nb: COR-2017-01 Cortendo AB
A Double-blind, Placebo-Controlled, Randomized Withdrawal Following Open-label Therapy Study to Assess the Safety and Efficacy of Levoketoconazole (2S, 4R ketoconazole) in the Treatment of Endogenous Cushing’s Syndrome |
2018- 2021
4 patients randomized |
Protocol 112025-002 HRA Pharma
Prospective, single arm, open-label, multicenter, international study to assess the effects of metyrapone in patients with endogenous Cushing’s syndrome during a 12-week treatment period followed by an extension period of 24 weeks |
2019- 2022
1 patient |
Protocol nb: XL184–311 EXELIXIS A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Cabozantinib (XL184) in Subjects with Radioiodine-Refractory Differentiated Thyroid Cancer Who Have Progressed after Prior VEGFR-Targeted Therapy |
2020- 2022
2 patients
|
Trial ID: EX9536-4388 Novo Nordisk
Semaglutide effects on cardiovascular outcomes in people with overweight or obesity (SELECT) |
2020- 2022
3 patients |
CORT125134-455 CORCEPT Glucocorticoid Receptor Antagonism in the Treatment of Cushing Syndrome (GRACE): A Phase 3, Double-Blind, Placebo-Controlled, Randomized Withdrawal Study of the Efficacy and Safety of Relacorilant. |
2021- 2023
8 patients |
CORT125134-456 CORCEPT Glucocorticoid Receptor Antagonism in the Treatment of Hypercortisolism in Patients with Cortisol-Secreting Adrenal Adenomas or Hyperplasia (GRADIENT): A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Relacorilant |
2021-
7 patients, recruiting |
CORT125134-452 CORCEPT “An Open-Label Extension Study of the Safety of Relacorilant (CORT125134) in the Treatment of the Signs and Symptoms of Endogenous Cushing Syndrome.” |
2021-
8 patients, recruiting |
SPR001- 203 MEDPACE “A Randomized, Double-Blind, Placebo Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of SPROO 1 (Tildacerfont) in Adult Subjects with Classic Congenital Adrenal Hyperplasia” |
2023-
1 patient |
SPR001- 204 MEDPACE “A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of SPR001 (Tildacerfont) in Reducing Supraphysiologic Glucocorticoid Use in Adult Subjects with Classic Congenital Adrenal Hyperplasia”” |
2023-
3 patients |
SPI-62-CL-2001 Sparrow Pharmaceuticals, Inc “SPI-62 as a treatment for Adrenocorticotropic Hormone dependent Cushing’s Syndrome” |
2023-
1 patient, recruiting |
SPI-62-CL-2002 Sparrow Pharmaceuticals, Inc “SPI-62 as a treatment for hypercortisolism related to a benign adrenal tumor” |
2023-
recruiting |